Sun Damage + Pigmentation

Sun-Card

fact1

2 in 5 people have a genetic variation that affects their skin’s UV defences.

The sun’s UV rays are one of the most significant causes of premature skin aging. Your genes play an important role in determining how well your skin can naturally cope under the strains of the sun.

uv-light

Exposure to ultraviolet (UV) light from the sun accounts for 90% of the symptoms of early skin aging, skin damage, and skin cancer. Every time your skin is exposed to UV light, skin damage occurs. The cumulative effect of repeated sun damage causes epidermal DNA damage, persistent inflammation, and oxidative stress, negatively affecting the health and appearance of your skin.

Our genetic predispositions play an important role in determining how your skin can naturally cope under the strains of the sun. The SkinDNA ™ Test can reveal if your skin has a greater or lesser natural genetic solar protection factor (gSPF™), and based on your results can provide you with a unique, enhanced skin care protection strategy that is specially designed to provide the utmost protection for your skin based on your genes.

Genetic Markers SkinDNA ™ Test for in this category.

Gene Table

SkinDNA™ Gene Descriptor Genotype Description
s600851
s600852/

Melanin Production
AA
GG
Involved in the production of Melanin. A process important for protecting the skin against the sun.
Chromosome Location: 19q13.2
s600623/
UV Repair
AA Repairs genetic damage caused by UV exposure.
Chromosome Location: 3q21.3
s600442
s600443/

Photo Defense
GG
CC
Functions in breaking down DNA photoproducts.
Chromosome Location: 19q13.3
s600931/
UV Radical Protection
AA Responsible for repairing DNA mutations caused by 8-oxo- G radicals.
Chromosome Location: 13q26.2

Develop a better understanding about SkinDNA ™ Genetic Test: Sun Damage + Pigmentation category.

Background Science

Every time the skin is exposed to UV light, some damage occurs and the cumulative effect of that repeated damage is epidermal DNA damage, persistent inflammation and oxidative stress.

uv1

Repeated exposure to ultraviolet light (UV radiation) from the sun accounts for nearly 90% of symptoms of early skin aging, skin damage and skin cancer. Oftentimes the harmful effects of the sun are a greater contributor to skin aging than all other factors combined, including the intrinsic aging of skin cells.

Symptoms of sun damage include: texture changes (coarse wrinkling and yellow discoloration), blood vessel changes (broken capillaries and Telangiectasias), pigment changes (age spots, brown spots, freckling), skin bumps (Kerasotes) and skin cancer. Sun damage can take years to surface often when the damage is too late.

Consistently preventing damage to skin caused by the sun’s UV rays should be the single most important aspect of your skin care strategy. Proper UV protection may not only help prevent photoaging and further damage to the skin but can also facilitate the reversal of some of the existing signs of aging.

Your genes play an important role in determining how well your skin can naturally cope under the strains of the sun. The SkinDNA ™ Genetic Test can reveal if your skin has a greater or lesser natural genetic solar protection factor (gSPF ™), and based on your results can provide you with a unique, enhanced skin care protection strategy that is specially designed to provide the utmost protection for your skin based on your genes.

Don’t know all of these terms? Our glossary may help…

Glossary

8-oxo-G radical
8-oxoG radical is considered to be one of the worst types of free radical species. This radical is generated by exposure to ionizing radiations such as UV light.
8-oxo-G radicals can cause harmful mutations within the DNA structure6 and can ultimately affect the functioning of crucial genes that play vital roles in collagen synthesis, protection and other central duties.

Melanin
Pigment (color) found in the skin. Melanin is essential in protecting the skin from the sun.
The release of melanin helps absorb and breakdown the sun’s harmful UV rays and UV-generated free radicals.5 The reason some people are darker than others is because of the amount of melanin their body naturally produces.

The more efficient the body is at producing melanin the more your skin is able to withstand (to a degree) the suns UV rays. Pigmentation has been widely viewed as a photoprotectant and research has shown that darkly pigmented skin is at a lower risk of photocarcinogenesis than fair skin.

Photoproducts
A form of DNA damage, they are chemical reactions that are produced by the action of light.
They are formed mainly from UV light omitted by the sun or by artificial means such as a Solarium. Photoproducts can account for one quarter of all DNA damage.